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Activ Surgical

Powering the Future of Surgery

Bibliography

ActivSight™ Enhanced Intraoperative Visualization

A bibliography of published clinical data and abstracts.

  1. Tully S, Oberlin J, DeMaio E, Dehghani H, O’Shea L, Calef T, Kim PC. Superior efficacy and utility of ActivSight laser speckle imaging to Indocyanine Green (ICG)-based fluorescence imaging in visualizing in vivo tissue perfusion and vasculature. Society of American Gastrointestinal and Endoscopic Surgeons 2020 Meeting

  2. Nwaiwu CA, Shah SK, Bajwa KS, Agarwal, AK, Felinski MM, Walker PA, Wilson TD, Holihan JL, Akhtar SJ, Kudav V, Rachlin EK, Rivera AR, Klein CL, Dechert AF, Buharin VE, Kim PCW, Wilson EB. First Thirty-Four Consecutive Patients Using De Novo Laparoscopy-Compatible Real-time Imaging Device Combining Laser Speckle Contrast Imaging and Near-infrared Fluorescence (NIRF) in Colorectal and Bariatric Surgery, and Laparoscopic Cholecystectomy (LC). Society of American Gastrointestinal and Endoscopic Surgeons 2021. Presentation date: August 31 –September 3, 2021

  3. Nwaiwu CA, Buharin VE, Mach A, Grandl R, Dechert AF, O’Shea LJ, Schwaitzberg SD, Kim PCW. Feasibility And Comparison of Laparoscopic Laser Speckle Contrast Imaging (LSCI) To Near-infrared (NIR) Display of Indocyanine Green (ICG) In Intraoperative Tissue Blood Flow/Tissue Perfusion and Extrahepatic Bile Ducts in Preclinical Porcine Models. American College of Surgeons Clinical Congress 2021. Presentation date: October 23, 2021

  4. Shah SK, Nwaiwu CA, Agarwal AK, Bajwa KS, Felinksi MM, Walker PA, Wilson TD, Dechert AF, Kim PCW, Wilson EB. First-In-Human (FIH) Safety, Feasibility, & Usability Trial (NCT# 04633512) Of A Laparoscopic Imaging Device Using Laser Speckle Contrast Imaging (LSCI) Visualizing Real-Time Tissue Perfusion and Blood Flow Without Fluorophore in Colorectal and Bariatric Patients. American College of Surgeons Clinical Congress 2021. Presentation date: October 24, 2021

  5. Noel JP, Mascarenhas A, Nwaiwu CA, Liu YZ, Buharin VE, Oberlin J, Dechert AF, Kim PCW, Patel V. ActivSight Laser Speckle Contrast Imaging Compared to Indocyanine Green in Renal Perfusion of an Animal Model. European Robotic Urologic Society 2021.

  6. Sanders CM, Nwaiwu CA, Liu YZ, Panchal AN, Butsch JL, Hoffman AB, Posner AR, Falvo MA, Visco J, Ortolani JB, Barone SM, Burstein MD, DeJesus C, Bouvy ND, Boni L, Shah SK, Wilson EB, Dechert AF, Buharin VE, Schwaitzberg SD, Kim PCW. ActivSightTM Dye-less Visualization of Tissue Perfusion in MIS Surgery: Interim Analysis of First Clinical (n=66) and Preclinical (n=20) Studies with ICG Comparison. World Congress of Endoscopic Surgery/ European Association of Endoscopic Surgery 2021. Presentation date: November 24, 2021

  7. Noel JP, Mascarenhas A, Nwaiwu CA, Liu YZ, Buharin VE, Oberlin J, Dechert AF, Kim PWC, Patel V. ActivSight Laser Speckle Contrast Imaging Compared to Indocyanine Green in Renal Perfusion of an Animal Model. American Urologic Association 2022.

  8. Boni, L. A novel visualisation system. European Association for Endoscopic Surgery Midwinter Meeting 2022.

  9. Mehrotra S, Liu YZ, Nwaiwu CA, Buharin VE, Oberlin J, Stolyarov R, Schwaitzberg SD, Kim PCW. Potential Clinical Utility of Real-Time Tissue Perfusion Quantification Using Laparoscopic Laser Speckle Contrast Imaging (LSCI) and Differential Responses to Arterial Versus Venous Occlusion in Porcine Intestine Model. Society of American Gastrointestinal and Endoscopic Surgeons 2022. Presentation date: March 16, 2022

  10. Liu YZ, Nwaiwu CA, Dechert AF, Mehrotra S, Shah SK, King ML, Schwaitzberg SD, Kim PCW, Wilson EB. Utility and Usability of Laser Speckle Contrast Imaging (LSCI) for Displaying Real-time Tissue Perfusion/Blood flow in Robot Assisted Surgery (RAS): Comparison to Indocyanine Green (ICG) Use and in Laparoscopic Surgery. Society of American Gastrointestinal and Endoscopic Surgeons 2022. Presentation date: March 17, 2022

  11. Rai, A; James, J; Richstone, A; Kavoussi, L. Evaluating Utility and Efficacy of Laser Speckle Imaging for Visualizing Perfusion During Urologic Surgery. Engineering and Urology Society 2022.

  12. Nwaiwu CA, Liu YZ, Mehrotra S, Wilson EB, Schwaitzberg SD, Park A, Kalady MF, Kim PCW. ActivSightTM: Real-time, Dye-Free Visualization of Bowel Perfusion Using Laser Speckle Contrast Imaging. American Society of Colon and Rectal Surgeons 2022. Presentation date: May 1, 2022

  13. Liu YZ, Mehrotra S, Stolyarov R, Nwaiwu CA, Oberlin J, Schwaitzberg SD, Kalady MF, Kim PCW. Quantifying Real-Time Bowel Perfusion & Distinguishing Arterial/Venous Obstruction using Laser Speckle Contrast Imaging (LSCI). American Society of Colon and Rectal Surgeons 2022. Presentation date: May 3, 2022

  14. Agarwal AK, Nwaiwu CA, Mehrotra S, Liu YZ, Sanders CM, Falvo MA, Wilson EB, Shah SK. Usability of Laser Speckle Contrast Imaging for Perfusion Assessment: First 17 Colectomy Patients. American Society of Colon and Rectal Surgeons 2022. Presentation date: April 30- May 4, 2022

  15. Mehrotra S, Liu YZ, Stolyarov R, Nwaiwu CA, Oberlin J, Schwaitzberg SD, Kim PC. Perfusion Difference in antimesenteric & mesenteric bowel with Laser Speckle Contrast Imaging. American Society of Colon and Rectal Surgeons 2022. E-poster.

  16. Liu YZ, Mehrotra S, Buharin VE, Oberlin J, Marois M, Nwaiwu CA, Filicori F, Wilson E, Kim PCW. Dye-less, Real-time Visualization of Tissue Perfusion in Porcine Gastric Tube Model using Laser Speckle Contrast Imaging (LSCI) and Laser Doppler Imaging (LDI). American Society for Metabolic and Bariatric Surgery 2022. Presentation date: June 9, 2022.

  17. Mehrotra S, Liu YZ, Buharin VE, Oberlin J, Marois M, Nwaiwu CA, Filicori F, Schwaitzberg SD, Wilson EB, Bouvy ND, Kim PCW. Relative Perfusion Response of Gastric Tube to Aortic and Portal Vein Occlusion Measured by Laser Speckle Contrast Imaging (LSCI) in Porcine Model. American Society for Metabolic and Bariatric Surgery 2022. E-poster.

  18. Liu YZ, Mehrotra S, Buharin VE, Oberlin J, Marois M, Nwaiwu CA, Bouvy ND, Kim PCW. Comparing Real-time Quantification of Tissue Perfusion using Laser Speckle Contrast Imaging to Laser Doppler Imaging in Porcine Intestinal Anastomosis. European Association of Endoscopic Surgery 2022. Presentation date: July 6, 2022.

  19. Liu YZ, Mehrotra S, Buharin VE, Oberlin J, Marois M, Nwaiwu CA, Chand M, Bouvy ND, Boni L, Kim PCW. Comparing Real-time Tissue Perfusion Assessment between Laser Speckle Contrast Imaging and Indocyanine Green Fluorescence in Porcine Small Intestine. European Association of Endoscopic Surgery 2022 – Amazing Technologies Session. Presentation date: July 5, 2022.

  20. Chibueze A. Nwaiwu, Mahdi Al-Taher, Roman Stolyarov, Yao Z. Liu, Saloni Mehrotra, Rainer Kimmig, Benjamin Weixler, Hans F. Fuchs, Manish Chand, Kai Nowak, Luigi Boni, Adrian E. Park, Nicole Bouvy. Quantifying Tissue Perfusion Using Laser Speckle Contrast Imaging and Correlation with Local Tissue Capillary Lactate. European Association of Endoscopic Surgery 2022 – Amazing Technologies Session. Presentation date: July 5, 2022.

  21. Liu YZ, Nwaiwu CA, Dechert AF, Mehrotra S, Shah SK, King ML, Schwaitzberg SD, Kim PCW, Wilson EB. Utility and Usability of Laser Speckle Contrast Imaging (LSCI) for Displaying Real-time Tissue Perfusion/Blood flow in Robot Assisted Surgery (RAS): Comparison to Indocyanine Green (ICG) Use and in Laparoscopic Surgery. Society of American Gastrointestinal and Endoscopic Surgeons 2022. Accepted in Surgical Endoscopy on July 4, 2022.